Workshop 4: Quantitative Biology of Cytoskeletal Mechanics

Workshop Overview

The physical properties of cells combine with biochemical events to drive cell behavior. The cytoskeleton is a major determinant of cell mechanics, and is of particular interest from a physical perspective because it provides an opportunity to learn how large scale mechanical properties arise from the interactions of large numbers of active subunits. This workshop is intended to advance physical models of the cytoskeleton by bringing together researchers who are modeling and measuring cytoskeletal mechanics, in an informal setting to discuss key open questions. What are the greatest challenges and opportunities of our field? Many different types of models of contractile actomyosin networks have been proposed. Can we articulate benchmarks for these models that will enable direct comparison of results? Are there common themes that emerge from mechanical models used in various scenarios (e.g. migration, division, tissue)? What is similar? What is different? What aspects are missing? Is there a consensus on experimental measurements of viscoelasticity and force? How do we bridge length scales from molecular to cellular force measurements? Can we come to a consensus on valid approaches to compare experiment and theory. Importantly, can we recommend how to best design experiments to constrain and test theoretical predictions? We plan to address these questions through a combination of interactive talks and brainstorming sessions.

Date and Location

October 22-24, 2015

Hilton O'Hare Airport, Chicago IL. 


Partial List of Speakers

Organizer:  Margaret Gardel, University of Chicago

Moumita Das  -  Rochester Institute of Technology
Enrique De La Cruz  - Yale University (Tentative)
Zvonimir Dogic  -  Brandeis University
Sophie Dumont -  UCSF
Alex Dunn - Stanford University
Margaret Gardel -  University of Chicago
Brenton Hoffman -  Duke University
Lisa Manning  - Syracuse University
Adam Martin  -  MIT
Alex Mogilner -  New York University
Dan Needleman - Harvard University
Jim Sellers - National Institutes of Health
Boris Shraiman -  UCSB
Sean Sun -  Johns Hopkins University
Julie Theriot - Stanford University
 

Travel Information for invited speakers and confirmed attendees.

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